Monday, October 31, 2011

Late for work, officer accused of going 120 mph

A Miami police officer is accused of driving 120 mph on a turnpike because he was late for his off-duty job working security at a school.

    1. C'mon ? what's not to like?

      Hoof it over to Facebook to join the weird news herd.

The Florida Highway Patrol says officer Fausto Lopez was arrested at gunpoint after leading police on a brief high-speed chase.

According to a police report, a trooper spotted a patrol car changing lanes in a dangerous manner earlier this month. The report says the patrol car ignored warnings to pull over and led a brief high-speed chase before stopping near Hollywood.

Miami police spokesman Delrish Moss told The Associated Press on Saturday that administrative action against Lopez depends on the outcome of the case.

Univision first reported the arrest.

Copyright 2011 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

Source: http://www.msnbc.msn.com/id/45088048/ns/us_news-weird_news/

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Aussie court ends Qantas strike, fleet grounding

Idle Qantas planes are reflected in a window at Sydney Airport in Sydney, Sunday, Oct. 30, 2011. Qantas Airways grounded all of its aircraft around the world indefinitely Saturday due to ongoing strikes by its workers. (AP Photo/Rick Rycroft)

Idle Qantas planes are reflected in a window at Sydney Airport in Sydney, Sunday, Oct. 30, 2011. Qantas Airways grounded all of its aircraft around the world indefinitely Saturday due to ongoing strikes by its workers. (AP Photo/Rick Rycroft)

Douglas and Diane Phillips of Dover, Del. say they are trying to book a flight on another airline after their Qantas flight to Melbourne the night before was canceled at Los Angeles International Airport in Los Angeles, Saturday, Oct. 29, 2011. Qantas Airways grounded its global fleet Saturday, suddenly locking out striking workers after weeks of flight disruptions. (AP Photo/Jason Redmond)

Australia Prime Minister Julia Gillard speaks to the media after Qantas Airways grounded its global fleet amid a bitter dispute with striking workers, stranding passengers around the world, during the Commonwealth Heads of Government Meeting (CHOGM) in Perth, Australia, Sunday, Oct. 30, 2011. (AP Photo/ Theron Kirkman)

A Qantas Airbus A-330 plane sits on the tarmac at the Ninoy Aquino International Airport Sunday Oct. 30, 2011 at suburban Pasay city, south of Manila, Philippines. Tens of thousands of stranded Qantas Airways passengers worldwide scrambled to get to their destinations Sunday after the airline abruptly grounded its global fleet over a dispute with striking workers. Australia's government sought a court order to force the flagship carrier's planes back in the air. (AP Photo/Bullit Marquez)

Qantas Airways customer service workers help passengers at Los Angeles International Airport as the airline grounded its global fleet locking out striking workers after weeks of flight disruptions Saturday, Oct. 29, 2011 in Los Angeles. (AP Photo/Jason Redmond)

(AP) ? An Australian court early Monday ended the strikes and employee lockout that had abruptly grounded Qantas Airways and stranded tens of thousands of passengers worldwide. The airline planned to speak soon on when flights will resume.

The arbitration court heard more than 14 hours of testimony from the airline, the Australian government and unions after the government called the emergency hearing Saturday. Workers have held rolling strikes and refused overtime work for weeks out of worry that some of Qantas' 35,000 jobs would be moved overseas in a restructing plan.

The unions wanted a temporary suspension of the employee lockout, but the airline said the strikes had been too devastating and it needed certainty to continue operating.

Tribunal President Geoffrey Giudice said the panel decided a temporary suspension would still risk Qantas' grounding its fleet in the future and would not protect the tourism and aviation industry from damage.

Qantas is the largest of Australia's four national domestic airlines, and the grounding affected 108 planes in 22 countries.

About 70,000 passengers fly Qantas daily, and would-be fliers this weekend were stuck at home, hotels, airports or even had to suddenly deplane when Qantas suspended operations. More than 60 flights were in the air at the time but flew to their destinations, and Qantas was paying for passengers to book other flights.

Qantas CEO Alan Joyce said before the panel ruled that the airline could be flying again within hours of a decision. He had estimated the grounding would cost the carrier $20 million a day.

German tourist Michael Messmann was trying to find a way home from Singapore on Sunday. He and his wife spent five weeks traveling around Australia but found their connecting flight home to Frankfurt suddenly canceled.

"I don't know the details of the dispute, but it seems like a severe reaction by the airline to shut down all their flights. That seems a bit extreme," said Messmann, 68. "After five weeks of traveling, we just want to go home."

Australian business traveler Graeme Yeatman sided with the airline, even though he was also trying to find a new flight home to Sydney on Sunday after his flight was canceled.

"I think the unions have too much power over Qantas. Even though this is an inconvenience for me, I'm glad the airline is drawing a line in the sand," said Yeatman, 41.

The airline infuriated unions in August when it said it would improve its loss-making overseas business by creating an Asia-based airline with its own name and brand. The five-year restructure plan will cost 1,000 jobs.

Qantas said in August it had more than doubled annual profit to AU$250 million but warned that the business environment was too challenging to forecast earnings for the current fiscal year.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/cae69a7523db45408eeb2b3a98c0c9c5/Article_2011-10-30-AS-Australia-Qantas/id-d5f61190bf5440e3bfd1fc65af8d3c47

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Sunday, October 30, 2011

Video: CNBC.com Market Outlook

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Source: http://www.msnbc.msn.com/id/21134540/vp/45082929#45082929

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Various kinds of Term Insurance Based on Who is Covered ? Cars ...

Apart from the insurer, there are three fundamental parties involved in life insurance deals such as term life insurance; the policy owner, the person insured and the beneficiary or beneficiaries in the case of multiple people being named as such on the policy. For instance, this can happen in the case of the last surviving parent leaving the proceeds to be divided among their children. The owner handles the policy and can make all of the actual decisions about beneficiaries, borrowing the cash value, selecting the type of negotiation options and pays the premium, etc. The Insured is the person whose life is covered and the beneficiary receives the proceeds from the policy when the insured person dies from a cause covered under the policy rules.

Term life insurance handles the insured for what is often a comparatively short period of time. All of the money from the premium is used to pay for the insurance itself. Consequently, after each term, the policy must be renewed. The policy does not accrue equity for the insured. There is no charges for not renewing a term life policy since the insurance organization is not in possession of an asset. If the covered dies during the term of the policy, the policy pays off at its face value. Term life policies are generally tax-free and might even enable a partial payout upon proper diagnosis of a terminal disease.

People choose term life once they need insurance for only a short period of time, or they require insurance, but can?t afford the premiums related to permanent insurance. Many people choose term life and then invest the main difference between the premium and a permanent life premium on their own. This type of person is confident that their investments will outperform those of the insurance organization.

Term life insurance can be classified based on who is covered. Group term insurance coverage is normally offered by employers. Group term life plans offer reduced premiums in exchange for insuring a large number of people. High risk term insurance plans are ideal for people of advanced age or with preexisting health conditions who cannot be eligible for a traditional coverage. Term insurance for kids is a life plan that protects those under the age of 18 usually covers things like funeral and burial expenditures.

Term insurance for households enables parents to add their kids to their plans at a minimal cost. For joint term life insurance, rather than paying much more to insure each spouse or partner separately, it protects both spouses with a single, inexpensive policy. Term life insurance for individuals is a policy that provides safety for those who are self-insured, or those who do not have access to employer-sponsored coverage. Term life insurance for people in the military is a type of life insurance for service members who often need life insurance urgently before deployments. Army term life can meet their unique needs. Term life insurance for seniors are insurance plans for senior citizens. Advanced age will not necessarily eliminate the potential of term life protection. Term life plans for seniors can offer considerable protection to those over the age of 50.

Term Life Insurance is regarded as the preferred form of Life Insurance today which gives protection for a guaranteed period of time. After all, that is what insurance is for: Protection for yourself and your loved ones.


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Tags: banking, business, education, family, finance, home, insurance, investment, legal, Personal, society
Topics: insurance

Source: http://carsandinsurance.info/insurance/various-kinds-of-term-insurance-based-on-who-is-covered

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Britain's Kate handles first solo royal engagement (AP)

LONDON ? Britain's royal family says the Duchess of Cambridge has handled her first solo duties since her wedding to Prince William ? acting as a last-minute stand-in for father-in-law Prince Charles at a charity dinner.

The young royal hosted an event Wednesday night in aid of In Kind Direct, a charity supported by the heir to the British throne, at London's Clarence House.

St. James's Palace said Thursday the duchess had been "delighted to be able to step in" and greet the 30 guests attending the reception.

Charles had traveled to Saudi Arabia for the state funeral of crown prince Sultan bin Abdul-Aziz Al Saud.

William and the duchess plan to travel to Denmark next week to visit a U.N. center that distributes emergency supplies to East Africa.

Source: http://us.rd.yahoo.com/dailynews/rss/celebrity/*http%3A//news.yahoo.com/s/ap/20111027/ap_on_en_ot/eu_britain_royals

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The9 launches new game channel to combat Android Market shutdowns in China

When the Android Market goes down in most places, people freak out for a couple of hours and then go back to their business until the next failure happens weeks or months later. In China, Market failures are more frequent and annoying since its outages last for days, not hours. Chinese gaming company The9 is launching its own Android app distribution channel, powered by OpenFeint , in order to combat the ?common disruption? caused by Market failures. Partnering with three Chinese carriers, The9 will set-up a Game Zone that enables smartphone users in China to have continued access to games during outages. ?Official Android shutdowns ?

?

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OpenFeint, the secret cross-platform sauce behind hundreds of Android games, has issued a press release today touting their new Game Channel for Android. Designed to both help players discover new games and highlight developers, it?s also a perfect opportunity for OpenFeint to thump their chest. ?We can?t blame them though as they have...? Samsung will be releasing the dual-screen SCH-W999 in China.?This phone features a five megapixel?rear-facing camera, Bluetooth 3.0?and a 3.5-inch 480 x 800 AMOLED display?accompanied?by three touch buttons. The inside packs a similar screen plus a physical keypad. The phone is powered by a MSM8660 chip and supports both GSM and CDMA2000 on...? At first glance, the HTC Sensation Z710t doesn?t differ much from the phone first introduced last spring, but underneath the familiar exterior lurks the new ST Ericsson NovaThor SoC. The handset is headed for China Mobile and couples the 1GHz Nova A9500 dual-core application processor with the Thor M6718 mobile for connectivity to the carriers...? Game Insight is known for its highly popular tycoon-style building games such as Paradise Island and My Country. Their newest release ?Rock The Vegas? has just recently hit the Android Market and puts users in control of building their very own Sin City. Do it your way by building unique casinos, bars, entertainment centers and any other...? Dell offers a small line of Android phones consisting of phones like the Mini 3i, Aero and Venue. Now Dell has officially announced a new Android powered phone known as the Dell Streak Pro but unfortunately the device is only exclusive to Japan, where it will be launched by Softbank. Dell faced some disappointing sales in the US and European markets...? Superplay Games, an independent team up of seasoned gaming developers and gamers, have released their first title this week. ?Called? Cosmonauts , it?s a free download for Android 2.0 or higher (most tablets) which lets players take turns against one another up in the stars. Featuring both single-player and multiplayer modes, the game offers...? Fresh off the Android Market is BET?s official 106 & Park app. To say the app is full-featured would be an understatement. This app goes above and beyond what you would expect from a simple app based off of a hit television show. Besides watching clips from the show and the hottest music videos, users can also interact with one another...? So far, today has been the day of ICS/Prime leaks, hasn't it? Yeah, and it's not over yet. The Android Developers YouTube account has all but confirmed that the official announcement is indeed coming on October 11th at Samsung's Unpacked event . Check it: So yeah, there's something else to add to the confirmed stack. Still though,...? Click here to view the embedded video. Modern Combat 3: Fallen Nation will be available soon on iOS and Android devices. ? Gameloft Modern Combat 3: Fallen Nation ? launch trailer originally appeared on AndroidGuys . Follow us on Facebook and Twitter ! ?Read More ? We received a number of emails this morning from excited Android users in the UK, advising that the Android Market now allows for movie rental. The move comes roughly one month after our friends up north started seeing rentals on phones and tablets. According to one email we received the Android Market notified him proactively that the update was available....?

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Source: http://feedproxy.google.com/~r/AndroidCenter/~3/KMAVNOdxQcY/

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Saturday, October 29, 2011

FIO, FOIA and a free market in insurance data

In the United States, publicly traded companies must file quarterly financial statements with the Securities and Exchange Commission, which the SEC makes available to the public through their EDGAR service.? Bank holding companies file their own quarterly performance reports with the Federal Reserve, which the Fed makes available to the public through its National Information Center.

The nation?s thousands of insurance companies also file annual and quarterly financial statements, covering everything from their premiums to claims to assets to investments. Because insurance is a state-regulated industry, these so-called ?statutory? financial reports are filed with the states in which the companies are domiciled. And these reports, too, are ultimately compiled by one central entity. But it is not a government agency, and it doesn?t release the results to the public.

At least, not for free.

The entity is the National Association of Insurance Commissioners, the private 501(c)(3) nonprofit group that acts as the collective political voice of the nation?s state insurance regulators. While the NAIC is not itself a regulator and has no statutory authority whatsoever, it nonetheless long has enjoyed a monopoly gatekeeper role for the reams of insurance financial data that are collected by state agencies using state taxpayer resources.

And insurance data is big business for the NAIC. According to the group?s just-released 2012 budget proposal,?there are now 400 million data elements in the NAIC?s Financial Data Repository, which is used as the primary source for some 193 NAIC publications and data products. The group projects it will earn $25.9 million in 2012 from database filing fees paid by the industry and another $18.9 million from sales of its insurance data products. Together, those items represent 57.3% of the group?s $78.2 million in projected 2012 revenues.

The major clients for the NAIC?s insurance data are market analytics firms like Charlottesville, Va.-based SNL Financial and insurance rating agency A.M. Best (Full disclosure: I have been, at different times, an employee at both firms) who repackage the information in a lucrative secondary market populated by banks, broker-dealers, asset managers and private investment funds. While big financial institutions make good use of the data, the rates charged by firms like Best and SNL tend to be well out of the price range of media and academic outlets who might do likewise.

And where a private stockholder interested in reading the financials of a company whose shares he owns can easily look up the company?s SEC filings, a private policyholder interested in, say, the reserves held by the insurer he has entrusted to protect his financial future?has essentially nowhere to turn.

But big changes could be in the offing, in the form of the new Federal Insurance Office created by the Dodd-Frank Act.? The brainchild of former Rep. Paul Kanjorski, D-Pa., FIO is designed to be a central repository of insurance expertise within the U.S. Treasury Department, empowered under the law to ?receive and collect data and information on and from the insurance industry and insurers; enter into information-sharing agreements; analyze and disseminate data and information; and issue reports regarding all lines of insurance except health insurance.?

Dodd-Frank is painstakingly specific in proscribing how FIO is to go about collecting the data it needs. To avoid duplicative reporting requirements, it must turn first to state or federal regulatory agencies, or to publicly available sources, before making any direct requests of insurers or their affiliates. The statute also specifies that confidentiality agreements between, for instance, regulated insurers and their state regulators (most often, those dealing with trade secrets) continue to apply even after that data has been transmitted to the federal office.? The office does have subpoena power to collect information should an insurer refuse to furnish it voluntarily, but the law sets a fairly high evidentiary bar for establishing that the subpoena is necessary.

Where the statute is considerably murkier is in what the office can, should or must do with the information it collects, which will presumably include the statutory financial reports currently filed with state regulators. The law establishes that the office can make information it collects available to state regulators through information-sharing agreements. It also specifies that entities (such as state insurance departments) that share information with the federal office that isn?t publicly available (such as statutory financial reports) retain ?any privilege arising under Federal or State law?to which the data or information is otherwise subject.?

What that would appear to mean in this context is that, if a state has exercised a privilege not to make statutory financial reports publicly available, it does not waive that privilege just because it has shared those reports with the federal office. What the law doesn?t appear to say is that the federal office is bound to exercise the same privileges with whatever information it receives.

Indeed, the federal Freedom of Information Act would appear to require the opposite.? Dodd-Frank actually specifies that Title 5 Section 552 of the U.S. Code (better known as FOIA) ?shall apply to any data or information submitted to the Office by an insurer or an affiliate of an insurer.? However, it is silent on whether information submitted to the office by state regulators is to be treated equally.

There are two ways to interpret this. Under the principle of expressio unius est exclusio alterius, the absence of state regulators from the list can be assumed to mean information they share is not covered by the statute. On the other hand, since non-confidential information transmitted from states to a federal agency generally would be covered by FOIA, it could simply be that no further clarification was necessary.

All of which is to say, it would appear the final decision on how to interpret the statute, and ultimately what to do with the data collected by FIO, will likely be made by FIO Director Michael McRaith himself.

We would urge him to come down on the side of transparency. Making insurers? statutory financial reports available through an open source, publicly accessible database is simply good public policy. It is in line with the spirit of Dodd-Frank, the spirit of FOIA and with the precedent set by other federal agencies who receive comparable financial statements from the financial services industry. It would bring to an end the absurd situation in which a private, nongovernmental entity is granted a monopoly over data collected with governmental resources, and would help alleviate suspicions that regulators? pecuniary interests to collect and sell ever more data could be driving public policy decisions.

Moreover, expanding public access to insurance data could have the added benefit of encouraging new or existing credit rating agencies to expand their monitoring of the financial strength of U.S. insurance companies, the vast majority of whom are mutuals that do not file disclosures with the SEC. As Terri Vaughan, the NAIC?s current CEO and a former state regulator herself, has said in defending the fragmented nature of state insurance regulation:

?In our state-based regulatory system, we have many eyes focusing on an issue, including some 13,000 people across the states,? she said. ?Because of that, we?re less likely to miss things and to come down on the side of dogmatic solutions.?

We would agree with Dr. Vaughan that markets work best when information is dispersed widely and shared freely. If the eyes of 13,000 state regulators represent a good start, then why not the eyes of the whole world?

Source: http://outofthestormnews.com/2011/10/27/fio-foia-and-a-free-market-in-insurance-data/

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What DARPA’s Scavenger Hunt Taught Us About Mobilizing People Fast

Disaster strikes. A hurricane or an earthquake hits a major city, taking out power stations and emergency-services communications. No one knows how many are dead and how many need immediate help. First responders need information, and they need it fast?not just about casualties, but also about what resources they can muster quickly. Emergency workers faced with such a situation have to cobble together whatever resources are available?after Hurricane Katrina, for example, rescuers relied on an ad hoc citizen-radio network to relay information. But there are smarter and better ways to mobilize lots of people in a hurry?as shown by an oddball scavenger hunt.

Two years ago, DARPA (Defense Advanced Research Projects Agency), the Pentagon?s mad-scientist department, celebrated the 40th anniversary of the Internet by issuing a challenge. It scattered 10 weather balloons in undisclosed locations around the U.S., promising to award $40,000 to the first team to find them all. Anyone could win, but rapid organization of team members scattered across the country would be essential. After all, someone who happened to be near one of the 8-foot-diameter bright red balloons would have no trouble spotting it, but the competing teams would need to connect those lucky bystanders to their own team as quickly as possible. Between the time DARPA announced the competition in late October and Dec. 5, the day of the contest, the MIT Red Balloon Team mobilized some 4400 team members to find all 10 balloons in just 8 hours 52 minutes.

The reason DARPA put on this curious contest was to find out the best way to get lots of people spread out over lots of space to work together. And this week, the MIT team reflected on just why their strategy worked so well. In the new edition of the journal Science, seven MIT team members describe their so-called "recursive incentive mechanism" in a paper titled "Time Critical Social Mobilization." Here?s what they learned about mass mobilization.

1. A Little Something for Everybody


Alex "Sandy" Pentland, director of MIT?s Human Dynamics Lab and co-author of the paper, says he and his MIT colleagues and students took on the challenge partly for fun, but partly for pride: His team?s research involves figuring out how to motivate groups of people to work together with maximum efficiency. To do it in the DARPA contest, the team dreamed ups its recursive incentive scheme, a way to break up the prize money into smaller chunks, and thereby motivate more people. The team promised to pay out the $40,000 prize money (if won, of course) in the form of incentives to each member of the team who found a balloon, as well as to each member who recruited a balloon finder, and who recruited a recruiter of a finder, and so on. The team?s organizers allocated $4000 total for each balloon, with payments starting at $2000 for a finder and being halved with each remove.

"I guess you could say it was a flash of insight," Pentland says. "But mostly it was obvious to us. When you think about how to use social networks to get people to work together, this is sort of the obvious thing to do. Apparently it wasn?t obvious to anyone else though."

2. People Don?t Hunt Balloons for Charity


The MIT group estimates there were between 50 and 100 other groups. Some used strategies that included offering to donate the entire $40,000 to charity if the team won, or recruiting key members who already had large followings on Twitter?hoping that would maximize the team?s reach. (Perhaps the problem was too many fake followers.) Lesson learned: Direct incentives trump altruism. In other words, people in these fast-mobilizing social networks say: Show me the money.

3. What About Real Life?


Team MIT?s following quickly swelled to its 4000-plus members from a core group of just four recruited from a website set up by the team. The team?s Science paper suggests that their organizing strategy could see applications ranging from mobilizing people for fight world hunger, for playing games, and for social media marketing.

But Pentland has much bigger ambitions. In addition to all of that, as well as for helping first responders react to disasters and emergencies, he sees "the rise of new types of companies and governments that are more agile and efficient." Agile because they would be formed around social networks rather than traditional top-down hierarchies. Efficient because they would be powered by incentives providing maximum motivation to participants rather than the plain old boring rules that govern most organized groups.

For now Pentland and team are focusing on a more mundane application: motivating people to exercise more. Participants in a new?project carry Android phones with?accelerometers?that track their degree of physical activity. A game on the phones rewards players with money for increasing their physical activity over time, with a catch. "Instead of giving you a reward for being more active," Pentland says, "we give your buddies a reward for your increase in activity." Players are thus encouraged to help each other to win, and that fosters cooperation for mutual benefit?the way the winning balloon-challenge scheme worked. "[Players] are finding it much more effective than standard techniques" for motivating themselves to get off the couch, he says.

Michael Belfiore is the author of The Department of Mad Scientists: How DARPA Is Remaking Our World, From the Internet to Artificial Limbs.

Source: http://www.popularmechanics.com/technology/military/research/what-darpas-scavenger-hunt-taught-us-about-mobilizing-people-fast?src=rss

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Video: Groupon Hits the Big Apple

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Source: http://www.msnbc.msn.com/id/21134540/vp/45077293#45077293

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Coroner: Winehouse died from alcohol

A coroner says Amy Winehouse died as the unintended consequence of drinking too much alcohol.

Coroner Suzanne Greenaway gave a verdict of "death by misadventure," saying the singer had voluntarily consumed alcohol and risked the consequences.

Story: Amy Winehouse's father is writing book

The singer, who had fought drug and alcohol problems for years, was found dead in bed at her London home on July 23 at age 27.

Slideshow: Amy Winehouse: 1983-2011 (on this page)

Pathologist Suhail Baithun told the singer's inquest Wednesday that Winehouse had consumed a "very large quantity of alcohol" and was more than five times over the legal drunk-driving limit when she died.

  1. More Entertainment stories
    1. 'Sister Wives' welcome baby No. 17

      And baby makes 22! According to People, Kody Brown and wife No. 4, Robyn, welcomed a baby boy on Wednesday morning. The child is the first for the couple, but is the 17th in the plural family.

    2. Report: Bruce Willis to be a dad again
    3. Exclusive: Taylor Armstrong shares healing
    4. 'Beavis and Butt-head' and ... Snooki?
    5. Trick-or-treat with a 'Toddlers' twist

The singer, who had fought drug and alcohol problems for years, was found dead in bed at her London home on July 23 at age 27.

An initial autopsy proved inconclusive, although it found no traces of illegal drugs in her system.

Story: Tony Bennett: Winehouse knew alcohol would kill her

Winehouse's doctor, Dr. Christina Romete, said the singer had resumed drinking in the days before her death after a period of abstinence.

Copyright 2011 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

Source: http://today.msnbc.msn.com/id/45045102/ns/today-entertainment/

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Friday, October 28, 2011

Scientists make strides toward drug therapy for inherited kidney disease

Scientists make strides toward drug therapy for inherited kidney disease [ Back to EurekAlert! ] Public release date: 27-Oct-2011
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Contact: Gail Gallessich
gail.g@ia.ucsb.edu
805-893-7220
University of California - Santa Barbara

(Santa Barbara, Calif.) Scientists at UC Santa Barbara have discovered that patients with an inherited kidney disease may be helped by a drug that is currently available for other uses. The findings are published in this week's issue of the Proceedings of the National Academy of Sciences.

Over 600,000 people in the U.S., and 12 million worldwide, are affected by the inherited kidney disease known as autosomal-dominant polycystic kidney disease (ADPKD). The disease is characterized by the proliferation of thousands of cysts that eventually debilitate the kidneys, causing kidney failure in half of all patients by the time they reach age 50. ADPKD is one of the leading causes of renal failure in the U.S.

"Currently, no treatment exists to prevent or slow cyst formation, and most ADPKD patients require kidney transplants or lifelong dialysis for survival," said Thomas Weimbs, director of the laboratory at UCSB where the discovery was made. Weimbs is an associate professor in the Department of Molecular, Cellular and Developmental Biology, and in the Neuroscience Research Institute at UCSB.

Recent work in the Weimbs laboratory has revealed a key difference between kidney cysts and normal kidney tissue. They found that the STAT6 signaling pathway previously thought to be mainly important in immune cells is activated in kidney cysts, while it is dormant in normal kidneys. Cystic kidney cells are locked in a state of continuous activation of this pathway, which leads to the excessive proliferation and cyst growth in ADPKD.

The drug Leflunomide, which is clinically approved for use in rheumatoid arthritis, has previously been shown to inhibit the STAT6 pathway in cells. Weimbs and his team found that Leflunomide is also highly effective in reducing kidney cyst growth in a mouse model of ADPKD.

"These results suggest that the STAT6 pathway is a promising drug target for possible future therapy of ADPKD," said Weimbs. "This possibility is particularly exciting because drugs that inhibit the STAT6 pathway already exist, or are in active development."

###


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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Scientists make strides toward drug therapy for inherited kidney disease [ Back to EurekAlert! ] Public release date: 27-Oct-2011
[ | E-mail | Share Share ]

Contact: Gail Gallessich
gail.g@ia.ucsb.edu
805-893-7220
University of California - Santa Barbara

(Santa Barbara, Calif.) Scientists at UC Santa Barbara have discovered that patients with an inherited kidney disease may be helped by a drug that is currently available for other uses. The findings are published in this week's issue of the Proceedings of the National Academy of Sciences.

Over 600,000 people in the U.S., and 12 million worldwide, are affected by the inherited kidney disease known as autosomal-dominant polycystic kidney disease (ADPKD). The disease is characterized by the proliferation of thousands of cysts that eventually debilitate the kidneys, causing kidney failure in half of all patients by the time they reach age 50. ADPKD is one of the leading causes of renal failure in the U.S.

"Currently, no treatment exists to prevent or slow cyst formation, and most ADPKD patients require kidney transplants or lifelong dialysis for survival," said Thomas Weimbs, director of the laboratory at UCSB where the discovery was made. Weimbs is an associate professor in the Department of Molecular, Cellular and Developmental Biology, and in the Neuroscience Research Institute at UCSB.

Recent work in the Weimbs laboratory has revealed a key difference between kidney cysts and normal kidney tissue. They found that the STAT6 signaling pathway previously thought to be mainly important in immune cells is activated in kidney cysts, while it is dormant in normal kidneys. Cystic kidney cells are locked in a state of continuous activation of this pathway, which leads to the excessive proliferation and cyst growth in ADPKD.

The drug Leflunomide, which is clinically approved for use in rheumatoid arthritis, has previously been shown to inhibit the STAT6 pathway in cells. Weimbs and his team found that Leflunomide is also highly effective in reducing kidney cyst growth in a mouse model of ADPKD.

"These results suggest that the STAT6 pathway is a promising drug target for possible future therapy of ADPKD," said Weimbs. "This possibility is particularly exciting because drugs that inhibit the STAT6 pathway already exist, or are in active development."

###


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Source: http://www.eurekalert.org/pub_releases/2011-10/uoc--sms102711.php

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MF Global shares plunge 40 pct on deep 2Q loss (AP)

NEW YORK ? Shares of MF Global Holdings Ltd. plunged more than 40 percent Tuesday afternoon after the broker reported its biggest-ever quarterly loss as a public company because volatile markets forced it to pull back on trading.

That raises questions about the plans of CEO Jon Corzine, former Goldman Sachs CEO and the former governor of New Jersey, for building MF Global into a bigger Wall Street player. Tough trading conditions are making that more difficult.

MF Global lost $186.6 million, or $1.16 per share, in the second fiscal quarter, far wider than the loss of $38.8 million, or 59 cents per share, in the same period a year ago. Weaker-than-expected trading revenues were partly to blame, though the company also took charges related to deferred tax assets, restructuring costs and paying down debt early.

Stripping out those charges, MF Global posted a loss of 9 cents per share, which still missed analysts' expectations for a 4-cent gain.

Revenue, after stripping out interest costs, sales commissions and other fees, fell 14 percent to $205.9 million. That was far short of analysts' expectations for about $302 million. The company blamed the lower revenue on its decision to scale back on its own trading activities.

"Reflecting the stressed markets in the quarter, we deliberately chose to reduce overall market exposure in most principal trading activities and focused on preserving capital and liquidity," Corzine said in a statement. Revenue in the principal trading group fell to $12 million from about $45 million.

MF Global, a broker-dealer in futures, commodities, foreign exchange and other markets, went public in 2007 and has been led since last year by Corzine. He has ramped up hiring to try to transform the broker into a global investment bank that manages money for customers and provides capital services for companies.

But in the past 12 quarters, the company has turned a profit three times, and shares are down nearly 75 percent this year.

News of the quarterly loss came a day after Moody's cut MF Global's credit rating over concerns about its exposure to European debt. Moody's analyst Al Bush said that he was increasingly concerned with MF Global's risk management strategies as it underwent a "substantial re-engineering of the firm." The analyst cited the company's increased exposure to European sovereign debt and its need to inject capital into its broker-dealer subsidiary to bridge a regulatory capital shortfall. Moody's cut MF Global's credit rating to its lowest investment-grade level.

"If market volatility stays elevated, we question how the firm is going to achieve the earnings necessary to avoid a downgrade of its debt to junk status, which in turn could materially impact its ability to act as a counterparty as well as raise MF's cost of debt," Raymond James analyst Patrick O'Shaughnessy wrote in a note to clients.

MF Global on Tuesday tried to address concerns about its exposure to indebted European countries including Belgium, Italy, Spain, Portugal and Ireland. Corzine said the company actively manages its investments.

"We remain confident that we have the resources and expertise to continue to successfully manage these exposures to what we believe will be a positive conclusion in December 2012," Corzine added.

Shares fell $1.69, or 48 percent, to close at $1.86 Tuesday. The stock fell to three-year low of $1.75 earlier in the day.

Source: http://us.rd.yahoo.com/dailynews/rss/earnings/*http%3A//news.yahoo.com/s/ap/20111025/ap_on_bi_ge/us_earns_mf_global

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Thursday, October 27, 2011

Mortgage applications bounced last week: MBA (Reuters)

NEW YORK (Reuters) ? Applications for home mortgages rose last week, recouping some of the steep decline a week before as demand for both purchases and refinancing perked up, an industry group said on Wednesday.

The Mortgage Bankers Association said its seasonally adjusted index of mortgage application activity, which includes both refinancing and home purchase demand, rose 4.9 percent in the week ended Oct 21.

The index had tumbled nearly 15 percent the week before.

The MBA's seasonally adjusted index of refinancing applications gained 4.4 percent, while the gauge of loan requests for home purchases was up 6.4 percent.

The refinance share of total mortgage activity eased to 77.3 percent of applications from 77.6 percent. Fixed 30-year mortgage rates averaged 4.33 percent, unchanged from the previous week.

The survey covers over 75 percent of U.S. retail residential mortgage applications, according to MBA.

(Reporting by Leah Schnurr; Editing by Diane Craft)

Source: http://us.rd.yahoo.com/dailynews/rss/personalfinance/*http%3A//news.yahoo.com/s/nm/20111026/bs_nm/us_usa_economy_mortgages1

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RV Polarstern launches 28th Antarctic season

RV Polarstern launches 28th Antarctic season [ Back to EurekAlert! ] Public release date: 27-Oct-2011
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Contact: Folke Mehrtens
medien@awi.de
0049-047-148-312-007
Helmholtz Association of German Research Centres

Bremerhaven -- On Friday, Oct. 28 2011 the research icebreaker Polarstern sets off on its 28th Antarctic expedition. Over 200 scientists and technicians from research institutions in 14 countries will take part in the five expedition legs. They will examine a wide variety of topics: oceanography and marine chemistry, atmospheric research and the biology of bacteria, tiny algae and animals all the way to crustaceans, fish and whales. Moreover, the Polarstern will supply Neumayer Station III in Antarctica with material, provisions and personnel.

The first leg of the expedition will take the vessel from Bremerhaven to Cape Town. On the way from the temperate latitudes through the subtropics and tropics researchers will investigate the material flows between ocean and atmosphere in the various climate zones. They want to find out more about how, for example, varying air humidity, cloud cover and temperature influence one another and how much radiation energy reaches the Earth's and the ocean surface. The incident radiation energy is the driving force for most physical processes in the Earth's climate system. On this leg, furthermore, technical scientific equipment (hydroacoustic, IT and communication systems, etc.) will be tried out, calibrated and tested. This is a major prerequisite for meeting the high demands placed on the measured data gained in this way.

Whales are a subject of study for the Oceanic Acoustics team at the Alfred Wegener Institute for Polar and Marine Research in the Helmholtz Association. Last year researchers for the first time put out a recorder that records whale songs around 700 kilometres off the coast of Namibia. Since visual observations of whales in the enormous oceans are rare, the bioacoustics experts wish to collect information on which species occur when in areas only presumed to be the mating grounds of blue and fin whales up to now. Since the behaviour-specific calls, such as during mating, are known, the researchers can also tell whether the whales are just passing through or really reproducing there. In this way they want to make a major contribution to learning more about the seasonal occurrence and reproduction behaviour of these baleen whales. This first leg of the expedition ends on 1 December 2011 in Cape Town, South Africa.

From there Polarstern will then head for Neumayer Station III in the Antarctic for supply and disposal purposes and then return to Cape Town from there. The following legs of the expedition in the Southern Ocean as of the beginning of 2012 will involve studies on the global carbon cycle. Interdisciplinary research teams will examine the physical, chemical and biological processes that drive the carbon pumps in the Southern Ocean and particularly in the numerous gyre systems there. Among other things, the focus will be on the role of microorganisms that play a significant role in carbon turnover. The investigations will also look at species diversity, distribution and frequency of animals and plants in the Antarctic deep sea. Additional calls at Punta Arenas (Chile) are planned before the Polarstern returns to its home port of Bremerhaven in May 2012.

###



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RV Polarstern launches 28th Antarctic season [ Back to EurekAlert! ] Public release date: 27-Oct-2011
[ | E-mail | Share Share ]

Contact: Folke Mehrtens
medien@awi.de
0049-047-148-312-007
Helmholtz Association of German Research Centres

Bremerhaven -- On Friday, Oct. 28 2011 the research icebreaker Polarstern sets off on its 28th Antarctic expedition. Over 200 scientists and technicians from research institutions in 14 countries will take part in the five expedition legs. They will examine a wide variety of topics: oceanography and marine chemistry, atmospheric research and the biology of bacteria, tiny algae and animals all the way to crustaceans, fish and whales. Moreover, the Polarstern will supply Neumayer Station III in Antarctica with material, provisions and personnel.

The first leg of the expedition will take the vessel from Bremerhaven to Cape Town. On the way from the temperate latitudes through the subtropics and tropics researchers will investigate the material flows between ocean and atmosphere in the various climate zones. They want to find out more about how, for example, varying air humidity, cloud cover and temperature influence one another and how much radiation energy reaches the Earth's and the ocean surface. The incident radiation energy is the driving force for most physical processes in the Earth's climate system. On this leg, furthermore, technical scientific equipment (hydroacoustic, IT and communication systems, etc.) will be tried out, calibrated and tested. This is a major prerequisite for meeting the high demands placed on the measured data gained in this way.

Whales are a subject of study for the Oceanic Acoustics team at the Alfred Wegener Institute for Polar and Marine Research in the Helmholtz Association. Last year researchers for the first time put out a recorder that records whale songs around 700 kilometres off the coast of Namibia. Since visual observations of whales in the enormous oceans are rare, the bioacoustics experts wish to collect information on which species occur when in areas only presumed to be the mating grounds of blue and fin whales up to now. Since the behaviour-specific calls, such as during mating, are known, the researchers can also tell whether the whales are just passing through or really reproducing there. In this way they want to make a major contribution to learning more about the seasonal occurrence and reproduction behaviour of these baleen whales. This first leg of the expedition ends on 1 December 2011 in Cape Town, South Africa.

From there Polarstern will then head for Neumayer Station III in the Antarctic for supply and disposal purposes and then return to Cape Town from there. The following legs of the expedition in the Southern Ocean as of the beginning of 2012 will involve studies on the global carbon cycle. Interdisciplinary research teams will examine the physical, chemical and biological processes that drive the carbon pumps in the Southern Ocean and particularly in the numerous gyre systems there. Among other things, the focus will be on the role of microorganisms that play a significant role in carbon turnover. The investigations will also look at species diversity, distribution and frequency of animals and plants in the Antarctic deep sea. Additional calls at Punta Arenas (Chile) are planned before the Polarstern returns to its home port of Bremerhaven in May 2012.

###



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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2011-10/haog-rpl102711.php

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U.S. says N. Korea talks positive, issues remain (Reuters)

GENEVA (Reuters) ? The United States and North Korea have narrowed differences in a second set of talks since wider negotiations on nuclear disarmament collapsed in 2009, but issues remain, the top U.S. negotiator said on Monday.

Ambassador Stephen Bosworth, U.S. special representative for North Korea policy, said the U.S. goal was to find a "solid foundation" on which to relaunch bilateral and multilateral talks with Pyongyang.

"We are moving in a positive direction. We have narrowed some differences but we still have differences that we have to resolve," Bosworth told reporters in Geneva after a first day of meetings and a dinner that he hosted for the North Korean delegation, led by First Vice Foreign Minister Kim Kye-gwan.

"We will continue to try to narrow differences," he added.

Bosworth said that the discussions had been very intensive but gave no clue as to where progress had been made or what areas remained problematic.

There was no immediate comment from North Korean officials who are to host the talks on Tuesday, including a possible joint lunch. Bosworth said he expected to make a statement after the talks conclude.

Earlier, Clifford Hart, U.S. special envoy for the stalled six-party talks, told reporters after the morning session that each side had made "useful presentations" of its position.

The session, which follows talks in New York in late July, is aimed more at managing tensions on the divided Korean peninsula than resuming stalled regional talks on ending the North's nuclear programs.

U.S. officials have described the talks as "exploratory" and aimed at keeping Pyongyang engaged so as to avoid any "miscalculations" by the reclusive nation.

State Department spokeswoman Victoria Nuland, speaking to reporters in Washington shortly before Bosworth's remarks, said the talks were proceeding "in a very businesslike fashion."

"In July, we gave the North Koreans a specific set of initiatives that we'd like to see to demonstrate that they are prepared to take concrete steps to meet their denuclearization obligations," Nuland said, saying the United States planned to follow up on all those issues during the current talks.

"Where are they now on their readiness to make concrete progress on their...nuclear responsibilities? How do they evaluate the first round of talks that they had with the...the South Koreans? ...Are they prepared to commit to continue this process?," she said.

SLIGHT EASING OF TENSIONS

U.S. officials and analysts were keeping expectations low, despite a slight easing of tensions between American ally South Korea and North Korea, and Pyongyang's repeated calls for resuming nuclear talks.

The six-party talks, including North Korea's ally China as well as Russia, Japan and South Korea, fell apart in 2009 when North Korea quit the process after U.N. sanctions were imposed following its second nuclear test.

China wants North Korea to deepen talks with the South and the United States in the hope of restarting nuclear negotiations, the Chinese vice premier told his North Korean counterpart, state media reported on Monday.

The six-party forum offers the North economic aid in return for dismantling its nuclear program which is believed to have yielded enough fissile material to make up to 10 atomic bombs.

Last year, the North unveiled a uranium enrichment facility at Yongbyon, which opens a second route to make a nuclear bomb along with its plutonium program, and argued it was for peaceful purposes. It says uranium enrichment falls outside the realm of previous six-party negotiations.

A September 2005 agreement reached by all sides does not specifically refer to uranium enrichment, only stating that the North must cease all nuclear activities.

Seoul and Washington insist that Pyongyang must first halt its nuclear activities, including its uranium enrichment program, before six-party talks can restart.

U.S. Defense Secretary Leon Panetta, on his first visit to Asia, said in an op-ed published in Japan's Yomiuri newspaper that the common challenges faced by the United States and Japan included North Korea and China.

South Korea said last week that Pyongyang's defiance over uranium enrichment remains the biggest hurdle.

North Korean leader Kim Jong-il has stated his readiness to return to the nuclear talks "without any preconditions." He says the North remains committed to fulfilling the September agreement with the aim of denuclearizing the entire peninsula.

(Reporting by Stephanie Nebehay; additional reporting by Arshad Mohammed in Washington and Phil Stewart in Japan; Editing by Michael Roddy)

Source: http://us.rd.yahoo.com/dailynews/rss/asia/*http%3A//news.yahoo.com/s/nm/20111024/wl_nm/us_korea_north_us

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Video: PFT Live: Can the Jags win AFC South?

Sorry, Readability was unable to parse this page for content.

Source: http://nbcsports.msnbc.com/id/21134540/vp/45034253#45034253

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Tuesday, October 25, 2011

Another strikeout for Virginia's children (hamptonroads)

Share With Friends: Share on FacebookTweet ThisPost to Google-BuzzSend on GmailPost to Linked-InSubscribe to This Feed | Rss To Twitter | Politics - Top Stories Stories, RSS Feeds and Widgets via Feedzilla.

Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/152920274?client_source=feed&format=rss

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Monday morning KO: A reminder of Matt Mitrione?s power

With Matt Mitrione taking on Cheick Kongo this Saturday at UFC 137, it's a good time to take a look back at how Mitrione ended his last fight. Here is a snippet of his bout with Christian Morecraft at UFC on Versus 4.

This fight will be Mitrione's toughest test yet. He is undefeated, with all of his fights have? in the UFC after a career in the NFL. Will Mitrione handle Kongo's striking? Tell us in the comments or on Facebook.

Source: http://sports.yahoo.com/mma/blog/cagewriter/post/Monday-morning-KO-A-reminder-of-Matt-Mitrione-s?urn=mma-wp8479

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Lessons from Sherlock Holmes: From Perspective-Taking to Empathy

Last week, I wrote about the importance of perspective-taking. This week, I?d like to continue with one of its close relatives, a state that would indeed be largely impossible without its existence: empathy.

Empathy, a concept originally introduced as Einf?hlung by Theodore Lipps, is a state that allows us to share in the experiences and mental states of others. It lets us understand?or at least begin to approximate?their feelings, their internal conditions, their possible thoughts and motivations, and as such, is one of the central elements of social behavior. And surprisingly, if you take his almost pathological detachment from others seriously?or obviously, if you consider both his remarkable ability to take on others? points of views and his emotional attachment, however veiled, to the select few?it is an ability that Sherlock Holmes demonstrates to great effect on multiple occasions, sometimes going as far as to side with the criminal over the law when he identifies enough with the circumstances of the crime. In one such instance, we find him at the end of ?The Adventure of Abbey Grange? urging Watson to stop a moment before rendering justice on Captain Jack Croker.

When Holmes makes his way to Scotland Yard to share crucial information with Inspector Hopkins on the murder under investigation, he changes his mind: he departs before entering the station and goes back to Baker Street having told nothing to the police. Why does he do that? As he tells Watson,

?No, I couldn?t do it, Watson. Once that warrant was made out, nothing on earth would save him. Once or twice in my career I feel that I have dome more real harm by my discovery of the criminal than ever he had done by this crime. I have learned caution now, and I had rather play tricks with the law of England than with my own conscience.?

When later that evening, Inspector Hopkins visits Baker Street with no more idea of the proper way to proceed than he?d had earlier on, Holmes dismisses him without much further explanation. He then addresses Watson:

?I dare say you thought I acted rather badly to Stanley Hopkins just now??

?I trust your judgment.?

?A very sensible reply, Watson. You must look at it this way: what I know is unofficial; what he knows is official. I have the right to private judgment, but he has none. He must disclose all, or he is a traitor to his service. In a doubtful case I would not put him in so painful a position, and so I reserve my information until my own mind is clear upon the matter.?

And when his own mind does clear up, after he and Watson listen to Croker?s account of events, he proceeds to take upon himself the role of judge and pronounce the man acquitted.

Of course, in this instance we are witnessing far more than empathy at work: we are seeing a detective ascertain the details of a case, and then decide that the crime was worth committing. But why? From where did that judgment arise?

Here, we can see Mr. Holmes empathizing with two individuals: Mary Fraser and Jack Croker. Because of Mary?s ill treatment at the hands of her husband, she was a victim and worthy of drastic interference; and because of the captain?s love for Mary, he, too, was a victim (of his passion) and an upholder of the chivalric code of honor (protecting his lady) that Sir Conan Doyle himself held so dear.

Holmes makes his judgments long before hearing the details of the case from Croker?s lips. From the moment he hesitates on the steps of Scotland Yard, he has placed himself on the side of the perpetrators, progressing from their mindsets, their motivations, their goals?not his own?in making his decision. In short, he demonstrates the very hallmarks of empathetic thinking. It?s a step beyond simple perspective-taking. True, Holmes must first take the perspective of those in question; but then, he emotionally identifies with them in a way that the more purely cognitive first step does not necessitate.

The origins of empathy

Where does such empathy come from? When we observe someone acting a certain way or exhibiting a certain emotion, we automatically mirror the action in our own minds. So, if we see someone smile, we enact that smile in our heads?and often, on our own faces. When we see them lift an apple, we imagine that action ourselves. And as we do so, we begin to grasp not just the hows but the whys of the action. Why is he smiling? Why is he taking an apple? He?s happy. He?s hungry. I begin to see where he?s coming from. It?s not yet empathy, but it?s a step in its direction.

Indeed, so basic is the process of mental imitation that even in a macaque monkey, observing another?s action activates identical neural firings as does performing that action. This accidental discovery, made in the 1980s by a team of Italian researchers led by Giacomo Rizzolatti, has since formed the basis for much of the research into models of empathy and empathetic behavior, though the exact relationship remains unclear. It seems that much of empathetic feeling comes from our minds mirroring back the actions of the world via the so-called mirror neurons (in reality, just specialized motor neurons that fire in response to others? actions). We don?t need to actually smile to model the smile in our minds?though we may do so anyway?and whether or not we physically perform an action, we are able to approximate its performance as if we had done so.

In a recent imaging study that attempted to untangle the mechanisms of imitation, individuals were shown images of different types of facial expressions (happy, sad, disgusted, surprised, angry, and afraid) while in a scanner. They either simply observed those expressions, or imitated them in addition to observing. The researchers found several interesting occurrences. First, the tasks engaged a largely overlapping neural network: even when individuals were just observing an emotion, the motor areas of the brain associated with performing the emotional action were activated, suggesting that internal imitation?a repetition of someone else?s action in your mind?was an essential component of experiencing empathy, even without physical mirroring. In order to emphasize with someone else, we must first mentally represent the actions that would be associated with the emotion that we see.

However, certain areas, namely the inferior frontal cortex (an area that codes action goals), superior temporal cortex (an area that codes early visual descriptions of actions and sends those descriptions to a specific subset of mirror neurons), and insula and amygdala (two areas heavily implicated in emotional processing), were in fact more active during the imitation trials than the observation trials. So, while we largely simulate similar reactions when we merely observe, actively imitating others? emotional states and engaging with them more completely may help explain that causal step from simple cognitive understanding (I know he smiled and I know what smiling feels like) to emotional understanding and engagement (I begin to sense why he?s smiling and I?m engaging myself with that emotion).

In fact, we are remarkably good at inferring an action?s goals as opposed to just observing the action itself, making the latter course of active engagement (where we imitate the smile and don?t just observe it) more attainable. We may even do so much more naturally. In one study, children were easily able to imitate the hand movements of an experimenter who was sitting across the table under normal circumstances, but began to make mistakes when two large red dots were placed on either side of the table. Now, whenever the experimenter moved a hand, it would cover a red dot, and the children began to imitate the goal of covering the dot as opposed to the motor action they had been instructed to follow; the former came much more instinctively. So, not only do we imitate quite naturally, but we begin to make inferences, assign states, make generalizations almost automatically as well. Even if we?re told not to think about goals and to focus on mechanics alone, the natural reaction is to do exactly what we?re not supposed to be doing anyway.

Developing empathy further

Perhaps, then, we can exploit such natural tendencies to develop our empathetic ability to the point where we are able to imagine ourselves letting a murderer go?simply because we understand where he?s coming from (of course, in real life this is a much more problematic proposition than in Holmes?s world, which tends to be far more clear-cut, but the principle of broader and deeper other-understanding itself is a worthy and valid one).

There is, for example, evidence that some people mimic behavior much more frequently than others; they then tend to identify more with the feelings of those others and, in turn, experience more compassion toward them. In other words, by being better imitators they become more empathetic individuals. We could use their example in trying to actively imitate others when we need to understand them and identify with them emotionally (perhaps part of what Holmes was accomplishing when, back in The Valley of Fear, he chose to return to the scene of the crime?).

There is also some indication that we tend to empathize more with close others than we do with more distant others, feeling their pain, to take one instance, more acutely. Another approach, then, may be to frame more people as closer to ourselves, members of our immediate in-group, and fewer as constituting out-group, further others.

And a final approach? It brings us right back to where we started: perspective-taking. Learning to simulate others? thoughts and actions from their own viewpoint and not ours, just as Holmes did with The Valley of Fear and as he does again in ?The Adventure of Abbey Grange.? In the latter instance, Holmes goes a step beyond what most people are capable of achieving, becoming the empathetic individual par excellence. In his understanding of Croker?s motives and actions, he exhibits empathy even without having ever seen the individual in question?a mirroring at a distance. He has mentally been able to put himself in someone else?s place, to embrace his perspective to such an extent that he can motivate a murder in the wake of its influence.

And that, in a sense, is the goal of empathy: to take ?mirroring? to its extreme, and instead of relying on those automatic, easy moments of imitation when something is staring us in the face, learning to use our powers of mental simulation on a deeper, broader, and more active level, empathizing at a distance and acting in accordance with that more open and accepting mental state.

Photo credit: Holmes and Watson welcome Captain? Jack Croker in ?The Adventure of the Abbey Grange.? By Sidney Paget (1860 ? 1908) (Strand Magazine) [Public domain], via Wikimedia Commons

Previously in this series:

Don?t Just See, Observe: What Sherlock Holmes Can Teach Us About Mindful Decisions
Lessons from Sherlock Holmes: Paying Attention to What Isn?t There
Lessons from Sherlock Holmes: Cultivate What You Know to Optimize How You Decide
Lessons from Sherlock Holmes: Perspective Is Everything, Details Alone Are Nothing
Lessons from Sherlock Holmes: Don?t Underestimate the Importance of Imagination
Lessons from Sherlock Holmes: Confidence Is good; Overconfidence, Not So Much
Lessons from Sherlock Holmes: The Situation Is in the Mindset of the Observer
Lessons from Sherlock Holmes: The Power of Public Opinion
Lessons from Sherlock Holmes: Don?t Tangle Two Lines of Thought
Lessons from Sherlock Holmes: Breadth of Knowledge Is Essential
Lessons from Sherlock Holmes: Don?t Decide Before You Decide
Lessons from Sherlock Holmes: Trust in The Facts, Not Your Version of Them
Lessons from Sherlock Holmes: Don?t Judge a Man by His Face
Lessons from Sherlock Holmes: The Importance of Perspective-Taking

Source: http://rss.sciam.com/click.phdo?i=b328cc289f4d1f2553ff973dd9f3da27

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